The fight is set to open the main card of the Zuffa Boxing show headlined by WBC welterweight champion Ryan Garcia's first title defense against Conor Benn at T-Mobile Arena in Las Vegas. The event will stream live on Paramount+ in the United States and DAZN in the United Kingdom and Ireland.

Magsayo (29-2, 19 KOs) made his Zuffa Boxing debut last time out against Feargal McCrory, a fifth-round stoppage win on April 5. "Magnifico" Magsayo, a 31-year-old from the Philippines, is a former WBC featherweight titleholder. He captured the crown in 2022 with a majority decision win against Gary Allen Russell Jr. but lost his following two fights, against Rey Vargas and Brandon Figueroa. Magsayo is currently on a five-fight winning streak.

“I’ve waited for a night like this my whole career. I signed with Zuffa to be on the biggest shows,” Magsayo said in a statement. “Andres Cortes called me out, and I answered. He won’t have his ‘0’ after I get done with him.”

Cortes (25-0, 13 KOs), a 29-year-old from Las Vegas, headlined the event Magsayo was last featured in and scored a 10-round unanimous decision win against Eridson Garcia.

“This is my opportunity to show the world what I can do. I’m going to destroy Mark Magsayo on September 12,” Cortes said in a statement. “Growing up in the gyms in Las Vegas, I dreamed of fighting on a platform like this in front of my people. The time has come.”

Zuffa Boxing also announced on Wednesday that Da’Mazion Vanhouter (12-0, 9 KOs) will face Raphael Akpejiori (19-3, 18 KOs) in an eight-round heavyweight bout as part of the prelim portion of the card.

The co-main event, which was announced last week, features Ring and Zuffa Boxing cruiserweight champion Jai Opetaia (30-0, 23 KOs) taking on WBC titleholder Noel Mikaelian (28-3, 12 KOs).