The boxing landscape will likely turn on its head Saturday.

A trio of high-stakes title bouts will take center stage, led by Teofimo Lopez defending his Ring and WBO junior welterweight championships against Shakur Stevenson in The Ring 6 headliner at New York's Madison Square Garden on DAZN PPV. Joining us to break down Saturday's biggest fights are The Ring's Manouk Akopyan, Matt Penn and John Evans.

Manouk: Carlos Adames vs. Ammo Williams could end in a knockout, but I'm not too sure who'll come away with the stoppage, even though Adames is listed as a minus-425 betting favorite. Adames has fought four times since 2022; Williams 11 times in that span. That's a lot of inactivity during Adames' prime, and it could show against the fresher and younger Williams.

Williams is there to get hit, as was proved again in his last fight against fight-week replacement Ivan Vazquez, but he hits back just as well. I expect a back-and-forth fight ending with a dramatic finish where the loser goes out on his shield.

Matt: The consensus on Lopez-Stevenson as a fight is that it will flatter to deceive. Both men are counterpunchers, but Lopez is a mercurial talent and personality, and his unpredictability can make this fight not only interesting but entertaining.

Stevenson is also moving up in weight, so there's a sense of unknown there and he'll be eager to record a real signature win against a high-profile opponent. Stevenson may want to assert his dominance physically and will have to fight more offensively to do so. I'm happy backing the evening's two most talented fighters to provide us with the most entertainment.

John: The WBC middleweight title fight between the aggressive Carlos Adames and the unpredictable Austin "Ammo" Williams looks like it will produce fireworks at some stage. The physical Adames will commit to his usual, aggressive approach and believe that he can wear down and break Williams over the fight's second half.

Williams will try to time Adames' charges, but he isn't the type of fighter to meekly accept his fate. If he feels the tide turning against him, the 29-year-old southpaw will dig his toes into the canvas and fire back. The middleweight division is in a state of change and both men will be desperate to ensure they remain in the shake-up.

Manouk: It's a tie between Lopez and Stevenson. Lopez can't afford to be dethroned by the smaller fighter moving up in weight, while Stevenson needs to shine in a star-making performance he's long-been promising.

The fight's winner will be set up for even more meaningful and lucrative matchups. But a loss for either isn't necessarily a bad thing as there are so many good fights to be made with the rest of the competition — the loser just has to deal with the endless jabs and jives.

Matt: Perhaps Xander Zayas. A 23-year-old Puerto Rican fighting at home in a world title unification, against someone as tough as Abass Baraou? Sounds like pressure to me.

John: I think Zayas will have the most weight on his shoulders. Top Rank is taking the 23-year-old home to Puerto Rico for the first time in almost six years, and a passionate support will assume he will beat the talented but relatively unknown Baraou in conclusive fashion.

Zayas has been groomed for stardom and has a lot of expectations to live up to.

Manouk: The betting odds don't reflect the 50-50 nature of this high-level chess match. Lopez has a history of rising to the occasion, and I envision him doing the same against Stevenson and forcing him to show the unseen levels of his game that he's alluded to during the pre-fight buildup.

I envision a nip-and-tuck first half and an explosive second half that ends in a split decision. I can't confidently predict who'll pull it off, and that's what makes this fight so intriguing.

Matt: Great fight. As far as a prediction goes, I’ll pick Stevenson. He’s Mr. Consistent, prepares the right way and looks mentally checked in every time, much like his good friend and mentor Terence Crawford. Lopez at his best, like he was against Vasiliy Lomachenko and Josh Taylor, will obviously cause major problems and this is his division. It’s just a question of whether that Lopez will turn up.

John: This is as good a pure boxing match as the sport can offer. It looks likely to become a high-quality, sharp-shooting contest with some dramatic, intense exchanges.

We already have evidence that Lopez can decode a master boxer after seeing him outwit Lomachenko, whilst Stevenson has proven time and time again that his ring IQ and defensive skills are amongst the very best. Lopez is too clever to allow Stevenson to fall into his easy, counterpunching rhythm and may try to force him into his shell early by landing something meaningful. If Lopez can't make a quick impression and Stevenson has time to study the problem in front of him, he will work out the answers quickly.

Fortunately for fans, both fighters are clever and skilful enough to react and change their tactics as the fight goes on. Lopez is the biggest man Stevenson has boxed but that doesn’t seem like it will play too big a part in the fight. I get the feeling that Stevenson will cement himself as one of boxing's elite talents with a closely fought decision.

Manouk: Zayas and Baraou are both unproven champions, so it's fitting they're facing each other in their respective first title defenses. The pressure is all on Zayas in his Puerto Rican homecoming, and we've seen how that can work against a champion, as Subriel Matias showed in his shocking loss against Liam Paro in 2024.

Baraou proved in his last fight against Yoenis Tellez that he can go on the road to pull off the upset. The winner will hold two of the four major titles and turn into incredible eye candy for uncrowned contenders Vergil Ortiz and Jaron Ennis.

Meanwhile, Bakhram Murtazaliev finally returns for the first time in 15 months after easily destroying Tim Tszyu. Another impressive stoppage will make Murtazaliev look like a world beater, hopefully not leading to another long layoff for the division's current boogeyman.

Matt: Honestly, I see them as pieces of Ennis' puzzle at 154. Ultimately, if "Boots" decides he wants to become an undisputed champion at 154, then it's mostly there for the taking. From the champions, WBC titlist Sebastian Fundora would provide him with his trickiest and toughest fight, in my opinion.

John: Of the four, Kelly has the most to gain. The Englishman has yet to score a win at world level but would deservedly gatecrash the top 10 with a shock victory.

Murtazaliev will expect to retain his IBF title. Although the Russian represents a hard night for anyone at 154 pounds, beating Kelly will likely do little to advance his standing or cause many to revise their thinking about how he would fare against the likes of Ortiz or Ennis.

The Zayas-Baraou winner will take root inside the top five. In an ideal world, the winner would consolidate and grow as a unified champion before facing the likes of Murtazaliev, Ortiz, Ennis or Fundora. In reality, they will immediately have a major target on their back.

Manouk: I'm really intrigued by the bout between Keyshawn Davis and Jamaine Ortiz. Davis has a lot of questions to answer after a disastrous weekend last time out, in which he was 4.3 pounds overweight for his planned fight against Edwin De Los Santos. Davis also admitted to abusing alcohol leading up to that fight, and he's now moving up a weight class with a new coach against an upset-minded Ortiz, who always rises to the occasion.

Ortiz gave Lomachenko and Lopez tough nights, and if Davis doesn't bring his A-game, a shocking loss could be in store.

Matt: Maybe Ortiz. He's only lost to Lomachenko, Lopez and is settled at the weight. Davis is more talented than Ortiz and should win, but we all know what happened last June. He also hasn't fought in a year, and is already talking about fighting at welterweight. It also might not help that he no longer has Brian McIntyre in his corner. But we shall see.

John: Although Lopez is a surprisingly large underdog in his fight with Stevenson, it would be no surprise if he found a way to win. Lopez is an elite operator with a championship mindset and is likely to be insulted that so many people believe he is the outsider.

Any man capable of beating Lomachenko over 12 rounds is a serious operator. And although he tends to box to the level of his opposition, Lopez will be on high alert for every second versus Stevenson.